In vitro cytotoxic activity of equine lymphocytes on equine herpesvirus-1 infected allogenic fibroblasts
نویسندگان
چکیده
منابع مشابه
Identification of equine herpesvirus-1 antigens recognized by cytotoxic T lymphocytes.
Equine herpesvirus-1 (EHV-1) causes serious disease in horses throughout the world, despite the frequent use of vaccines. CTLs are thought to be critical for protection from primary and reactivating latent EHV-1 infections. However, the antigen-specificity of EHV-1-specific CTLs is unknown. The aim of this study was to identify EHV-1 genes that encode proteins containing CTL epitopes and to det...
متن کاملA critical view on Equine Herpesvirus-1 and on Equine Herpesvirus-associated Myeloencephalopathy (EHM)
An infection with Equine herpesvirus type 1 (EHV-1), officially and by convention now called EQUID Herpesvirus, is the cause for Equine herpesvirus-associated Myeloencephalopathy or EHM. In 2008 the USDA declared this syndrome an ‘emerging disease’ among horse populations in the U.S.A., which indicates that EHM is perceived as an expanding problem that is observed more frequently when compared ...
متن کاملEffect of a Histone Demethylase Inhibitor on Equine Herpesvirus-1 Activity In Vitro
Equine herpesvirus type 1 (EHV-1) is a ubiquitous and highly contagious pathogen that causes a range of disease severities with outbreaks of notable economic impact. Given the limitations in immune protection of current vaccines and the limited effectiveness of antiviral drugs on EHV-1 infections in vivo, improved treatment measures are needed to control disease. The use of drugs that alter the...
متن کاملEquine herpesvirus-1 consensus statement.
Equine herpesvirus-1 is a highly prevalent and frequently pathogenic infection of equids. The most serious clinical consequences of infection are abortion and equine herpesvirus myeloencephalopathy (EHM). In recent years, there has been an apparent increase in the incidence of EHM in North America, with serious consequences for horses and the horse industry. This consensus statement draws toget...
متن کاملEpidemiology of equine herpesvirus 2 (equine cytomegalovirus).
The epidemiology of equine herpesvirus 2 was examined by using restriction endonuclease DNA fingerprints to distinguish viruses isolated from two groups of horses. The first group consisted of three yearlings isolated from other horses but in contact with each other for 418 days, whereas the second comprised seven mares and their foals, which were sampled at monthly intervals from parturition u...
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ژورنال
عنوان ژورنال: Veterinary Immunology and Immunopathology
سال: 1996
ISSN: 0165-2427
DOI: 10.1016/0165-2427(95)05548-7